Infectious Disease in Humans

1559-102:
Discipline: Biology
Instructor: Campbell
Credits: 3
Day: A
Start: 1425
End: 1540
Field Work: Day 6 - Cape Town - 2 April | South Africa Download Syllabus

Prior to the discovery of the ‘sulpha’ drugs, penicillin and streptomycin in the first half of the 20th century, infectious diseases regularly killed huge numbers of human beings. Epidemics of bubonic plague, consumption, dysentery, influenza, and typhoid fever swept across Europe and Asia; such epidemics still strike continental Africa and South America. In the last seventy years improved public health and the availability of anti-pathogenic drugs have greatly reduced this loss of human life. Poor husbandry of our arsenal of antibiotics, however, has resulted in the development of massive and wide-spread pathogen resistance. Humankind thus now faces a return to the pre-1940 state-of-affairs; humanity is again at risk.

In this course we will look at the microbiology, etiology, management, and social impact of six infectious diseases (influenza, HIV/AIDS, cholera, tuberculosis, malaria and the tineas). Necessary biological background will be provided where appropriate, e.g. the anatomy/physiology of the human respiratory, digestive, circulatory, integumentary and immunological systems. We will also look at antibiotic discovery and mode-of-action, and explore why bacterial resistance to antibiotics arose so rapidly. Around Ghana we will find time to discuss yellow fever and schistosomiasis.

Field Work

Country: South Africa
Day: 6 - Cape Town - 2 April

Participants will visit the Tygerberg Children’s Hospital, home of the Hope Cape Town Association. Hope Cape Town is a nonprofit organization which offers community outreach, education and counseling focusing on HIV/AIDS and TB in the Western Cape Province of South Africa.  Tygerberg Children’s Hospital provides specialty pediatric care for infants with HIV/AIDs, TB or various cancers. The lab will feature a presentation by the Director of the Association. Through this experience participants will gain insight into HIV/AIDS and poverty in South Africa and the implications on families and societies.  Please plan ahead to bring one or two items to donate to Tygerberg Children’s Hospital.

Suggested items to donate include: new or gently used stuffed animals, clothing (0-5 years), toothbrushes and toothpaste, soft baby blankets.